Balto's son Kodi works for the US Mail. Kodi loves his job and his new friends Dusty, Kirby and Ralph. Balto is intrigued by the new bush plane that has arrived in Nome. He wishes to fly, just like the plane. When the pilot Duke offers to take the place of the mail-dogs, Kodi and his friends are worried about losing their jobs. They have a resentment against the pilot. Meanwhile, Boris falls for a female goose named Stella. She asks him to fly with her, but Boris is afraid of heights. He waits until the last moment before he eventually lies to her, claiming that he's suffering from numerous injuries that prevent him from flying. A race is organised between the dog-sled team and the bush plane. Kodi wants his father to lead his team. Balto is not so sure, but after a little convincing from Jenna, he accepts the offer. Not long afterwards, Duke discovers Balto exploring his plane. The two become friends, for Duke knows about how Balto saved the children. The next day, the race is about to begin. Boris boasts to Balto about how he's lied to Stella, unaware that she's right behind him. She becomes very angry and manages to get him stuck in one of the mail bags, which is hoisted onto the plane. The race begins to the town of White Mountain and back. At first, the plane easily overtakes the dogs. But on the way back, the plane mysteriously disappears. The dog team wins the race, and Kodi is confident that his job is secure. But Balto still doubts it, much to his son's dismay. When the plane still hasn't arrived yet, Balto suspects that something has gone wrong. He sets out to rescue Duke, but Kodi refuses to help, saying that Duke is the enemy because he tried to take away Kodi's job. After Balto leaves, Jenna is surprised and angry that Kodi had not gone to help and valued his job over a human life. Kodi realises that it is his duty to help his father. On the way, Balto meets up with Stella, who says that Boris was on the plane too. Stella is angry with Boris, but she is also missing Boris and admits that she was the one who chased him into the mailbag. With the help of Stella, and Muk and Luk, Balto locates the site of the crash, but not before encountering two angry moose. Boris is quickly found, and Stella and the polar bears head for home. Balto stays behind. He finds Duke (whose leg is broken) and tries to haul him back to Nome on a sheet of metal. But on the way back, an ice bridge that Balto is crossing breaks under his feet. Balto and Duke are about to fall into a canyon, but Kodi and his friends arrive just in time to save them both. The dogs help bring Duke back to Nome and Balto is praised as a hero, once again. Stella eventually forgives Boris, and Duke builds a new plane called "Balto Flyer" which Balto flies in with Duke.
- Casper, Wendy, Jazmine Payne, Carly Shay, Spencer Shay, Freddie Benson, Sam Puckett, Gibby, Nigel Baker, Kyle Baker, Mike Baker, Mark Baker, Jessica Baker, Kim Baker, Sarah Baker, Jake Baker, Henry Baker, Lorraine Baker, Cooper, Dylan Schenk, Ben Hilton, Jamie, Max, Becca, Nicky, Jeannie, The Flash/Tony, Crispin, Dylan, Duncan, Sean, Tony's Brother, Juel, Erin, Shirley Temple, The Barney & Friends and the Gang, German Speaking Boy, The Chipmunks (Alvin, Simon, and Theodore), The Chipettes (Brittany, Jeanette, and Eleanor), Aldo, Ethan, Miarissa, Bina, Ely, Otter, Tilly, Tom, Tiny, Ramona, Tina, Teddy, Denise, Derek, Harry, Rusty, Walter, Max, Sharkboy, Lavagirl, Linus, Marissa, Ely, Otter, Bindi, Rosie, Kelly, Lynn, Annie, Molly, Pepper, Duffy, Kate, July, The Fraggle Rock Gang, Andy, Ruby, Gracie, Kyle, Chyna Parks, Olive Doyle, Fletcher Quimby, Lexi Reed, Cameron Parks, Nat Wolff, Alex Wolff, Thomas Batuella, Allie DiMeco, David Levi, Qaasim, Cooper Pillot, Jesse Draper, Michael Jackson & Friends, Michael Jackson Badder, Spanky, Stymie, Froggy, Porky, Buckwheat, Uh-Huh, Waldo, Mary-Ann, Jane, Rascals #1, 2, 3, and 4, Friends of Stymie and Uh-huh, Darla, Alfalfa, Little Carbon Soldiers, Becky O'Shea, Junior Floyd, Jake Berman, Rudy Zolteck, Tad Simpson, Hanon, Marcus, Timmy Moore, Nubie, Johnny Vennaro, Briggs, Patterson, Priscilla O'Shea, Murphy, Keith, Marcus, Hector, Jessica, Lisa, Shock, Pete and Pete, Pablo, Tyrone, Tasha, Uniqua, Austin, Paul, The Oslen Twins, Calvin Cambridge, Murph, Ox, Marlon, Reg Stevens, Max Keeble, Megan, Robe, Kevin McCallister, Alex, Leah, Matilda, Penelope, Matthew, Dwayne, Steve, Robert, Nelly K., Sonny, Tawni Hart, Chad Dylan Cooper, Nico Harris, Grady Mitchell, Zora Lancaster, the Baby-Sitters Club gang, Simba, Nala, Timon, Pumbaa, Baloo, Kovu, Kiara, Uncle Max, Ma, Taran, Princess Eilonwy, Fflewddur Fflam, Gurgi, Jesse Greenwood, Elvis, Randolph Johnson, Nadine, The Goonies (Mikey Walsh, Brand Walsh, Mouth Devereaux, Data Wang, Chunk Cohen, Andy Carmichael, Stef Steinbrenner, and Sloth Fratelli), Scooby-Doo, Shaggy Rogers, Fred Jones, Daphne Blake, Velma Dinkley, Yogi Bear, Boo-Boo Bear, Snagglepuss, Huckleberry Hound, Quick Draw McGraw, Augie Doggie and Doggie Daddy, Wally Gator, Magilla Gorilla, Top Cat, Peter Potamus, Woody Woodpecker, Ttark, Toaster, Lampy, Radio, Blanky, Kirby, Fievel Mousekewitz, Tiger, Tony Toponi, Tanya Mousekewitz, Yasha Mousekewitz, Papa Mousekewitz, Mama Mousekewitz, Charlie Barkin, Itchy Itchiford, Hubie, Rocko, Jack Skellington, King Louie, Genie, Louis, Sebastian, Alex, Marty, Melman, Gloria, King Julien, Maurice, Mort, Roger Rabbit, and The Entire LionKingHeart Fantasy Films team and the rest of the characters will guest star in this film.