Ryan, Winnie The Pooh & The Gang Meets The Nutty Professor II: The Klumps is another Kids World crossover that will been sequel by 20th Universal Goodtimes Century Paramount. It is unknown when to appear on YouTube in the future.
Sherman Klump is working on a new miracle formula– this time, the fountain of youth. He is also preparing to marry a fellow scientist, Denise Gaines (Janet Jackson). Unfortunately, he has started suffering from personality lapses that are threatening to alienate his bride-to-be: against his will, he acts like the obnoxious, hypersexed Buddy Love of the first film. After a particularly unpleasant incident, Sherman goes to his lab to analyze his DNA and locates Buddy Love's DNA in an abnormal gene. He decides to use Denise's genetic research methods to isolate the gene and permanently extract Buddy Love's DNA from his own. His assistant, Jason, tries to stop him, warning him that he might damage his health or even lose his intelligence. Sherman disregards the warning and, alone in his lab late at night, extracts Buddy's DNA. The orphaned DNA, a glowing blob of jelly, combines with a hair from a basset hound named Buster and grows spontaneously into an adult man, Buddy Love—now a fully autonomous being. Thanks to his doggy heritage, however, this Buddy Love has a tendency to chase cats and cars. Sherman, meanwhile, has inflicted so much genetic damage on himself by removing Buddy that his brain cells begin dying at an exponential rate. Buddy breaks into the Klump's house and steals some of Sherman's youth formula (not before being mouth-kissed by Granny), planning to sell it to the highest bidder, then adds a household chemical to the remainder of the mixture. When Sherman administers the adulterated potion to a hamster in front of a large audience, the hamster, Petey, grows to enormous size. The Dean (Miller) hides from Petey under a fur coat, which the hamster sees as a female. Petey performs a lewd act (offscreen) on the Dean. After the fiasco, the deeply traumatised Dean fires Sherman. However, this is the least of Sherman's problems; his brain damage is now reaching a critical level. With the help of his loyal lab assistant, Jason, he devises a strategy to restore his mind. He plans to reintegrate Buddy into his DNA by reverting him back to the jelly-like matter he used to be, then sucking him up through a straw. Sherman concocts a new, stronger youth formula when he is interrupted by Dean Richmond, demanding to know what Sherman's playing at. Richmond explains Buddy Love is selling the youth formula to a rival company, and believes Sherman to be in on it. Sherman gets a tennis ball, and heads with Dean Richmond to the office where Buddy is pitching the youth formula he stole; if he can revert Buddy to an infantile state and consume him, the return of Buddy's DNA to his own system will repair the damage that he originally caused. When Sherman arrives Buddy laughs, but Sherman then throws the tennis ball, and Buddy's dog genes compel him to give chase. Sherman has coated the ball with his new, super potent youth formula, and when Buddy catches the ball, he turns into a toddler. He runs off, then melts into a gelatinous blob that continues fleeing. Finally, Buddy dies when he evaporates into a public coin fountain. But unfortunately, for Sherman, he can no longer get back inside of him. Denise and Cletus arrive, and see Sherman and Richmond. Sherman, before his brain becomes seriously damaged, sadly tells Denise, whom he no longer recognizes, that he no smart, never, no more. Denise starts crying, and one of her tears lands on the dried blob, causing it to trickle into the fountain. As his companions begin to usher him away, Denise promising to take care of him, Sherman turns and mumbles something about "pretty water". They see the fountain's water glowing a bright neon blue. Buddy is dead but his DNA is still alive in the water. She and Cletus force Sherman to drink the water before the DNA disperses, and he rapidly regains his mental faculties. In the last scene, Sherman and Denise get married.
- Bobby, Cindy, Oliver, Greg, Marcia, Peter, Jan, DJ, Stephanie, Michelle, Malcolm, Mallory, Resse, Renee, Dewey, Daisy, Alvin, Simon, Theodore, Brittany, Jeanette, Elanor, Sarah Baker, Jake Baker, Henry Baker, Kim Baker, Jessica Baker, Mark Baker, Mike Baker, Lorraine Baker, Nigel Baker, Kyle Baker, Spanky, Stymie, Froggy, Porky, Buckwheat, Uh-Huh, Waldo, Mary-Ann, Jane, Darla, Alfalfa, Aldo, Ethan, Marissa, Bina, Ely, Otter, Lau, Mick, Naoko, Becky O'Shea & The Little Giants Gang, Tommy, Dil, Chuckie, Phil, Lil, Kimi, Angelica, Susie, Harold, Nicole, Z, Patty, Katie, Robby, Brian, Pepper, Molly, Duffy, Kate, July, Tessie, Vada, Thomas J., Dennis The Menace & Friends, Shake It Up: Camp It Up (Flynn and his friends), Casper, Wendy, Jazmine Payne, Carly Shay, Spencer Shay, Freddie Benson, Sam Puckett, Gibby, Nigel Baker, Kyle Baker, Mike Baker, Mark Baker, Jessica Baker, Kim Baker, Sarah Baker, Jake Baker, Henry Baker, Lorraine Baker, Cooper, Dylan Schenk, Ben Hilton, Jamie, Max, Becca, Nicky, Jeannie, The Flash/Tony, Crispin, Dylan, Duncan, Sean, Tony's Brother, Juel, Erin, Shirley Temple, The Barney & Friends and the Gang, German Speaking Boy, The Chipmunks (Alvin, Simon, and Theodore), The Chipettes (Brittany, Jeanette, and Eleanor), Aldo, Ethan, Miarissa, Bina, Ely, Otter, Tilly, Tom, Tiny, Ramona, Tina, Teddy, Denise, Derek, Harry, Rusty, Walter, Max, Sharkboy, Lavagirl, Linus, Marissa, Ely, Otter, Bindi, Rosie, Kelly, Lynn, Annie, Molly, Pepper, Duffy, Kate, July, The Fraggle Rock Gang, Andy, Ruby, Gracie, Kyle, Chyna Parks, Olive Doyle, Fletcher Quimby, Lexi Reed, Cameron Parks, Nat Wolff, Alex Wolff, Thomas Batuella, Allie DiMeco, David Levi, Qaasim, Cooper Pillot, Jesse Draper, Michael Jackson & Friends, Michael Jackson Badder, Spanky, Stymie, Froggy, Porky, Buckwheat, Uh-Huh, Waldo, Mary-Ann, Jane, Rascals #1, 2, 3, and 4, Friends of Stymie and Uh-huh, Darla, Alfalfa, Little Carbon Soldiers, Becky O'Shea, Junior Floyd, Jake Berman, Rudy Zolteck, Tad Simpson, Hanon, Marcus, Timmy Moore, Nubie, Johnny Vennaro, Briggs, Patterson, Priscilla O'Shea, Murphy, Keith, Marcus, Hector, Jessica, Lisa, Shock, Pete and Pete, Pablo, Tyrone, Tasha, Uniqua, Austin, Paul, The Oslen Twins, Calvin Cambridge, Murph, Ox, Marlon, Reg Stevens, Max Keeble, Megan, Robe, Kevin McCallister, Alex, Leah, Matilda, Penelope, Matthew, Dwayne, Steve, Robert, Nelly K., Sonny, Tawni Hart, Chad Dylan Cooper, Nico Harris, Grady Mitchell, Zora Lancaster, the Baby-Sitters Club gang, Simba, Nala, Timon, Pumbaa, Baloo, Kovu, Kiara, Uncle Max, Ma, Taran, Princess Eilonwy, Fflewddur Fflam, Gurgi, Jesse Greenwood, Elvis, Randolph Johnson, Nadine, The Goonies (Mikey Walsh, Brand Walsh, Mouth Devereaux, Data Wang, Chunk Cohen, Andy Carmichael, Stef Steinbrenner, and Sloth Fratelli), Scooby-Doo, Shaggy Rogers, Fred Jones, Daphne Blake, Velma Dinkley, Yogi Bear, Boo-Boo Bear, Snagglepuss, Huckleberry Hound, Quick Draw McGraw, Augie Doggie and Doggie Daddy, Wally Gator, Magilla Gorilla, Top Cat, Peter Potamus, Woody Woodpecker, Ttark, Toaster, Lampy, Radio, Blanky, Kirby, Fievel Mousekewitz, Tiger, Tony Toponi, Tanya Mousekewitz, Yasha Mousekewitz, Papa Mousekewitz, Mama Mousekewitz, Charlie Barkin, Itchy Itchiford, Hubie, Rocko, Jack Skellington, King Louie, Genie, Louis, Sebastian, Alex, Marty, Melman, Gloria, King Julien, Maurice, Mort, Roger Rabbit, and The Entire LionKingHeart Fantasy Films team and the rest of the characters will guest star in this film.