The plot of the film is almost completely different from the 1964 TV-special, as are the songs.
Ryan, Winnie The Pooh, Roary the Racing Car The Fraggle Rock Gang, Ash Ketchum, Misty, Brock, Pikachu, Togepi, Littlefoot, Cera, Ducky, Petrie, Spike, SpongeBob SquarePants, Patrick Star, Bloom, Stella, Flora, Musa, Tecna, Layla, Roxy, Simba, Timon, Pumbaa, Zazu, Terk, Tantor, Baloo, Bagheera, King Louie, the Vultures (Buzzie, Flaps, Ziggy, and Dizzy), Jiminy Cricket, Alex, Marty, Melman, Gloria, the Penguins of Madagascar (Skipper, Kolwalski, Rico, and Private), Genie, Louis, Roger Rabbit, Danny, Sawyer, Rex, Dweeb, Woog, Esla, Rapunzel, Pascal, Flynn Rider, Maximus, Jean-Bob, Speed, Puffin, Chanticleer, Wilbur the Albatross, Owen, Lindsay, Beth, Strawberry Shortcake and her friends, Danny Phantom, Sam Manson, Tucker Foley, Jazz Fenton, Danny, Sawyer, Jean-Bob, Speed, Puffin, Rex, Dweeb, Woog, Elsa, Rapunzel, Pascal, Flynn Rider, Maximus, Chanticleer, Wilbur the Albatross, Bob the Tomato, Larry the Cucumber, Junior Asparagus, Hercules, Megara, Philoctetes, Pegasus, Alice, Pocahontas, Meeko, Flit, Princess Aurora, Prince Phillip, Peter Pan, Tinkerbell, Rosetta, Silvermist, Idressa, Fawn, Oliver, Dodger, Lucky, Cadpig, Rolly, Spot the Chicken, Woody, Buzz Lightyear, Jessie, Tommy Pickles, Chuckie Finster, Simon, Theodore, Brittany, Huckle, Lowly, Woody Woodpecker, Ord, Cassie, Arthur Read Bobby, Cindy, Oliver, Millicent, Greg, Marcia, Peter, Jan, Matthew, Dwayne, Steve, DJ, Stephanie, Michelle, Alex and Nicky, Teddy, Aaron, Denise, Derek, Harry, Rusty, Walter, Casper, Wendy, Kevin McCallister, CeCe, Rocky, Davis, Kelly, Lynn, Pebbles, Bamm-Bamm, Davey, Goliath, Tommy, Dil, Chuckie, Phil, Lil, Kimi, Angelica, Susie, Savannah, Nichole, Z, Doggie Howser, Cake, Miracle, Amy, Benjamin, Alex, Leah, Buffy, Jodi, Little Carbon Soldiers, Vada, Ryan, Noak, Thomas J., Mary Ann, Kaia, Jane, Gina, Teddy Bear, Jack B. Nibble, Little Bo Peep, Baa, Baa Sheep, Mary Quite Contrary, Eep Mouse, Gobo, Red, Mokey, Wembly, Boober, The Doozers, Pablo, Tyron, Tasha, Uniqua, Austin, Flynn, Gunther, Tinka, Leo Little, Carly, Sam, Freddie, Spencer, Kimmy Gibbler, Shirley Temple, Gibby, Daniel Cook, Emily Yeung, Gabriella, Gerald, May, Sid, Alvin, Simon, Theodore, Brittany, Jeanette, Elanor, Millie, Geo, Bot, Caillou, Leo, Sarah, Rosie, Clemintine, Julie, Andre, Jason, Jeffory, Jonus, Emma, Xavier, Billy, Gilbert, The All That Gang, Hannah Montana, Miley Stewart, Lilly, Lola, Oliver Oken, Mike Standley III, Jackson, Robby, Rico Suave, Malcolm, Mallory, Resse, Renee, Dewey, Daisy, Chyna Parks, Olive Doyle, Fletcher Quimby, Lexi Reed, Cameron Parks, Becky O'Shea, Junior Floyd, Jake Berman, Rudy Zolteck, Tad Simpson, Hanon, Murphy, Marcus, Timmy Moore, Nubie, Johnny Vennaro, Briggs, Patterson, Priscilla O'Shea, Debbis O'Shea, Calvin Cambridge, Murph, Ox, Marlon, Reg Stevens, Spanky, Stymie, Froggy, Porky, Buckwheat, Uh-Huh, Waldo, Mary-Anne, Jane Twin #1 & 2, Darla, Alfalfa, Tessie, Sharkboy, Lavagirl, Max, Linus, Marrisa, Nigel, Kyle, Mike, Mark, Jessica, Kimberly, Sarah, Jake, Henry, Lorraine, Cooper, Dylan Schenk, Quinn, Aldo, Ethan, Marrisa, Bina, Ely, Otter, Lau, Mick, Christina Beardsley, Harry Beardsley, Michael Beardsley, Kelly Beardsley, Phoebe, Naoko North, Joni North, Jimi North, Paisley Houndstooth, Darryl Parks, Roxanne Parks, Becky Murtaugh, Kenneth Murtaugh, Elliott Murtaugh, Daniel Murtaugh, Lisa Murtaugh, Robin Murtaugh, Bindi, Rosie, Matilda, Lavender, Bruce, Arena, Ben Hilton, Jamie, Max, Becca, Nicky, Jeannie, The Flash/Tony, Crispin, Dylan, Duncan, Sean, Tony's Brother, Juel, Erin, Twist, Kiki, Marina, Shout, Dragon, Alligator, Ostrich, Beaver, Cat, Mailmouse, Dennis Mitchell, Joey, Gina, Margaret, Gunther, Hector, Jessica, Lisa, Keith Watson, Marcus Barnes, Susan Evers, Sharon McKendrick, Sharon Ferris, Susan Carey, Hallie Parker, Annie James, Kady Jay Kyle, Franklin Aloyisious Mumford & Friends, Peter Pan, Wendy Darling, John Darling, Michael Darling, Slightly, Nibs, Curly, Twin #1 & 2, Tiger Lily, Tootles, Messenger Boy, Young Wendy, Young Skeeter, Madeline, Aggie, Victoria, Chantel, Lucinda, Serena, Sylvette, Veronica, Lolo, Julie, Beatrice, Taylor, Jackson C., Madeline Riggs, Morgan Riggs, Derek Venturi, Casey MacDonald, Richelle, Reese Ambler, Rydell, Becky, Kimberly, Dylan and their friends, Lizzie MacDonald, Edwin Venturi, Marti Venturi, Vicki, Truman French, Tina Kathleen Miller, Ramona, Beezus, Cory Baxter, Newton Livingston III, Meena Paroom, Sophia Martinez, Haley, Nat Wolff, Alex Wolff, Thomas, David, Qaasim, Cooper Pillot, Jesse Draper, Tanner Boyle, Ahmad Abdul Rahim, Amanda Wurlitzer, Engelberg, Jose Agilar, Regi Tower, Miguel Agilar, Kelly Leak, Ogilvie, John, Peter, Quinn, Jimmy Feldman, Rudi Stein, Tony Thompson, Rudolph Sackville-Bagg, Anna Sackville-Bagg, Gregory Sackville-Bagg, Timmy Lupus, Eric, Charlie, Nicole, Dena, Jared, Riley, Stacy, Kenny, Lauren, Anthony, Robin, Ana, Haylie, Ryan, Connie, Gloria, Flip, Devyn, Mickey, Richie, Annie, Jamal Jenkins, Lenni Frazier, Alex Fernández, Gaby Fernández, Tina Nguyen, Rob Baker, Héctor Carrero, Casey Austin, CeCe Jenkins, Greg, DJ, Malcolm, Daniel Cook, Stan Marsh, Kyle Broflovski, Eric Cartman, Kenny McCormick, Alex, Marty, Melman, Gloria, King Julien, Maurice, Mort, Terk, Tantor, Taran, Princess Eilonwy, Fflewddur Fflam, Gurgi, Orddu, Orgoch, and Orwen, Aladdin, Princess Jasmine, Abu, Genie, Iago, Brer Rabbit, Jesse Greenwood, Elvis, Randolph Johnson, Nadine, Fievel Mousekewitz, Tiger, Tony Toponi, Tanya Mousekewitz, Yasha Mousekewitz, Papa Mousekewitz, Mama Mouskewitz, Ariel, Flounder, Sebastian, The Goonies (Mikey Walsh, Brand Walsh, Mouth Devereaux, Data Wang, Chunk Cohen, Andy Carmichael, Stef Steinbrenner, and Sloth Fratelli), Baloo, Bagheera, King Louie, Manny, Sid, Diego, Charlie Barkin, Itchy Itchiford, Sasha, Fu Dog, Kenai, Koda, Rutt and Tuke, Roger Rabbit, Mickey Mouse, Donald Duck, Goofy, Scrooge McDuck, Huey, Dewey and Louie, Webby, Bugs Bunny, Daffy Duck, Resse, Ryndall, Robin Hood, Little John, Wilbur the Albatross, Mrs. Brisby, Jeremy the Crow, Jean-Bob, Speed, Puffin, Ttark, Woody Woodpecker, Slimer, Stay Puft, Toaster, Lampy, Radio, Blanky, Kirby, Jimmy Neutron, Carl Wheezer, Sheen, Cindy Vortex, Libby, The Muppets (Kermit the Frog, Fozzie Bear, The Great Gonzo, Miss Piggy, Rowlf the Dog, Scooter, The Eletric Mayhem, Rizzo the Rat, and Walter), Fred Flintstone, Wilma Flintstone, Pebbles Flintstone, Dino, Barney Rubble, Betty Rubble, Bamm-Bamm Rubble, George Jetson, Jane Jetson, Judy Jetson, Elroy Jetson, Astro, Rosie the Robot, Mr. Spacely, Yogi Bear, Boo-Boo Bear, Snagglepuss, Huckleberry Hound, Quick Draw McGraw, Augie Doggie and Doggie Daddy, Wally Gator, Magilla Gorilla, Top Cat, Peter Potamus, Scooby-Doo, Shaggy Rogers, Fred Jones, Daphne Blake, Velma Dinkley, Scrappy-Doo, Rex, Woog, Elsa, Dweeb, Jack Skellington, Kids World's Adventures Team travel back to the North Pole and first meet a baby reindeer named Rudolph, who is born with an abnormally red, shiny nose to Blitzen and his wife, Mitzi. His parents, Roary and the others start to worry that Rudolph will be made fun of because of this, and their worries come true when the secret of their son's nose is accidentally revealed to Rudolph's three uncles, Comet, Cupid, and Dasher, along with the rest of the residents of the North Pole.
Meanwhile, two of Santa's elves Doggle and Boone cross the bridge of the wicked Ice Queen, Stormella to deliver mail and accidentally crash into and destroy several ice statues that belong to her. When Stormella finds out, she closes her ice bridge to the public as punishment, and if anybody dares to cross it, she threatens to create a blizzard so strong it will render Santa unable to deliver presents to children around the world.
A year later, Rudolph is sent to school, where he is ridiculed by everybody around him with the exception of Zoey, a female reindeer that he falls in love with. Rudolph eventually runs away from school because of all the teasing and meets Santa, who accepts him despite his nose and treats him with kindness. Shortly after, on Christmas Eve, after Santa has flown away for his annual travel around the world, Rudolph winds up running into Zoey but Rudolph's mean cousin Arrow who has also set his sights on Zoey, disrupts their romantic moment beneath the mistletoe and tells Zoey to come with him instead which she reluctantly does but as she leaves she smiles over at Rudolph making him realise that she likes him.
Years later, Rudolph has reached adolescence and is about to take part in the Reindeer Games. Zoey gives her pendant to Rudolph to bring him good fortune, much to the chagrin of Arrow, who is now in a relationship with Zoey. Arrow cheats at the games so he may be chosen to become a Flyer (one of the reindeer who pulls Santa Claus's sleigh) so during the big race he trash talks Rudolph, making his nose gleam and blind Arrow. Rudolph wins the race, but is disqualified because his glowing nose is considered cheating. The disqualification of Rudolph infuriates both Blitzen and Zoey, who confronts Arrow for cheating and ends their romantic relationship. Rudolph overhears Blitzen arguing with the coach of the Reindeer Games that his son's nose was "an accident," attempting to persuade the referee that there was no way Rudolph could have controlled his nose's glow and avoided blinding Arrow but Rudolph misinterprets it to believe that his parents are ashamed of him. He decides to run away. Roary gets Rudolph to stop and says he and his whole team will all go together with him to run away, too.
Zoey is devastated upon learning that Rudolph, Roary and the others ran away from home, so she runs off in search of them and even deliberately crosses the forbidden bridge of Stormella, who incarcerates her in an icy prison cell.
Meanwhile, Rudolph, Roary and the others have become acquainted with an Arctic fox named Slyly (who is Rusty's uncle) and a polar bear named Leonard (who is Penny Ling and Buttons' uncle). Rudolph also meets the Sprites of the Northern Lights, a group of singing, colorfully garbed sprites who fly around the North Pole. They tell Rudolph that he must rescue the kidnapped Zoey. They instruct him how to properly use his nose, and Rudolph, Leonard, Slyly, Roary and the others journey to Stormella's castle to free Zoey.
Stormella fulfills her vow and unleashes a humongous blizzard upon the North Pole using her magical powers. Rudolph, Slyly, Leonard, Roary and the others make it to her castle, but soon find themselves locked up in ice prisons of their own. After the Ice Queen goes to sleep, Slyly sneaks into her bedroom and retrieves the key to his friends' prisons. However, Stormella wakes up and sends her pack of wolves after Rudolph and his friends, cornering them on a cliff. When she threatens to freeze Zoey, Rudolph uses his nose to blind Stormella, sending her toppling off of the cliff, hanging on for dear life. Rudolph saves Stormella's life by allowing her to grab on to his budding antlers and pulls her back up on the cliff, and the grateful Stromella offers to grant him a wish. Much to the Ice Queen's dismay, Rudolph wishes that Stormella would turn from evil to kindhearted.
Stormella does indeed have a change of heart but the snowstorm that she created is unstoppable. Boone and Doggle, who were sent to search for Rudolph, Zoey, Roary and the others, bring the entire group back to Santa's Village. However, because of the blizzard Santa is unable to carry out his flight this year but when he catches a glimpse of Rudolph's nose, Santa asks him to lead his team, to which he agrees. Santa also asks Roary if he and his whole team can help him deliver the presents around the world, to which he and the others all agree. With Roary and his whole team helping Santa delivering the presents, Rudolph guides Santa's sleigh through the storm, and receives a hero's welcome when he returns and it turns out to be a merry Christmas after all.
- At the very end of this movie, Rudolph the Red-Nosed Reindeer (1998 version) joins Kids World's team.
- Slyly is revealed to be Rusty's uncle while Leonard is revealed to be Penny Ling and Buttons' uncle.